KREMENOPOULOS MINAS MD, PhD, MSc

FLU IN CHILDREN: A NEW OPTION WITHOUT INJECTION

Annual influenza vaccination is a basic preventive measure in childhood. In recent years, in addition to the classic injectable vaccines, a...

KREMENOPOULOS MINAS MD, PhD, MSc

PEDIATRICIAN - THESSALONIKI - CENTER

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FLU IN CHILDREN: A NEW OPTION WITHOUT INJECTION

Annual influenza vaccination is a key preventive measure in childhood. In recent years, in addition to the classic injectable vaccines, a newer form of administration has been added, specifically aimed at children: the intranasal influenza vaccine.

From the autumn 2025, this specific option is also available in Greece, allowing vaccination without the use of a needle.

How it works

Unlike injectable vaccines, intranasal:

  • contains live attenuated viruses

  • acts locally in the nasopharynx

  • activates the immune defense from the "entrance gate" of the virus

Administered with nasal spray, in a very small amount, without pain or injury.

What ages is it aimed at?

The vaccine can be used in children from 2 to 18 years old.
Its application is given priority to children 2–5 years old, an age group for which there is also compensation.

In older children, vaccination is possible, but it is done without cost coverage.

Why would a family prefer it?

For many children, fear of injections is an obstacle to vaccination. The intranasal form:

  • reduces stress and resistance

  • facilitates the child's cooperation

  • quickly applied in the doctor's office

At the same time, it is a vaccine with long experience of use internationally and well-documented safety profile.

When it is not a suitable option

Due to its composition, it is not recommended for children with:

  • recent episodes of wheezing

  • known bronchial asthma

  • immunosuppression conditions

  • long-term treatment with salicylates

In these cases, protection against influenza is achieved by: injectable flu vaccines.

The available vaccination options

Today, the pediatrician can choose between:

  • injectable inactivated vaccines

  • cell culture vaccines

  • intranasal vaccine 

The choice is made individually, based on the child's history.

When is the right time?

Influenza vaccination is recommended before the start of the seasonal outbreak, ideally from mid-October to late November.
If this is not possible, it can be done later in the winter.

How many doses are needed?

  • Usually enough one dose

  • In younger children who have not had previous full immunization, booster shots are required. two doses with a distance of 28 days

If the intranasal vaccine is not available for the second dose, it can be given with injectable vaccine.

Safety and precautions

Vaccination is postponed in case of:

  • febrile illness

  • a serious allergic reaction to a component of the vaccine

Final thoughts

The ability to get vaccinated without a shot is changing the way many children approach the process. The intranasal flu vaccine offers a modern and reliable solution, especially useful at younger ages.

The final decision is always made in collaboration with the pediatrician, who evaluates the benefits and indications for each child individually.

KREMENOPOULOS MINAS MD, PhD, MSc
PEDIATRICIAN - THESSALONIKI - CENTER

Dr. Minas Kremenopoulos is a graduate of the School of Medicine of the Aristotle University of Thessaloniki (AUTH) with a specialization in pediatrics and a special research and clinical interest in neurodevelopmental disorders of newborns-infants-children and in child nutrition.

KREMENOPOULOS MINAS MD, PhD, MSc

PEDIATRICIAN - THESSALONIKI - CENTER

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*The content in this blog is not intended as a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of qualified health care providers with questions you may have about medical conditions.

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KREMENOPOULOS MINAS MD, PhD, MSc

PEDIATRICIAN - THESSALONIKI - CENTER

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